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2015. 9. 5. 20:11

[2015-June-22] FDA approves new antiplatelet drug used during heart procedure

http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm452172.htm





Kengreal.cdx


Anthony H. Ingall, John Dixon, Andrew Bailey, Mandy E. Coombs, David Cox, Judith I. McInally, Simon F. Hunt, Nicholas D. Kindon, Barry J. Teobald, Paul A. Willis, Robert G. Humphries, Paul Leff, Jane A. Clegg, James A. Smith, and Wendy Tomlinson, Antagonists of the platelet P2T receptor:  a novel approach to antithrombotic therapy, J. Med. Chem., 1999, 42 (2), pp 213–220

http://dx.doi.org/10.1021/jm981072s


Nicholas B. Norgard, Cangrelor: a novel P2Y12 receptor antagonist, Expert Opin. Investig. Drugs200918 (8), pp 1219-1230

http://dx.doi.org/10.1517/13543780903136708


Shawn M. Bauer, ADP receptor antagonists as antiplatelet therapeutics, Expert Opin. Emerging Drugs20038 (1), pp 93-101

http://dx.doi.org/10.1517/14728214.8.1.93


Satya P. Kunapuli, Zhongren Ding, Robert T. Dorsam, Soochong Kim, Swaminathan Murugappan, and Todd M. Quinton, ADP receptors-targets for developing antithrombotic agents, Curr. Pharm. Design, 2003, 9 (14), pp 2303-2316

http://dx.doi.org/10.2174/1381612033453947


Alan D. Michelson, Antiplatelet therapies for the treatment of cardiovascular disease, Nat. Rev. Drug Discov.20109 (2), pp 154-169

http://dx.doi.org/10.1038/nrd2957


S. M. A. Fayaz and G. K. Rajanikant, A critical appraisal of the functional evolution of P2Y12 antagonists as antiplatelet Drugs, Curr. Pharm. Design, 2012, 18 (12), pp 1625-1634

http://dx.doi.org/10.2174/138161212799958558


Maria Lukasik and Michal K. Owecki, Efficacy of antiplatelet treatment in stroke prevention: past, present, and future, Drug Dev. Res.201374 (7), pp 428–439

http://dx.doi.org/10.1002/ddr.21100


Nicola Ferri, Alberto Corsini, and Stefano Bellosta, Pharmacology of the new P2Y12 receptor inhibitors: insights on pharmacokinetic and pharmacodynamic properties, Drugs201373 (15), pp 1681-1709

http://dx.doi.org/10.1007/s40265-013-0126-z


Elisabetta Liverani, Laurie E. Kilpatrick, Alexander Y. Tsygankov and Satya P. Kunapuli, The role of P2Y12 receptor and activated platelets during inflammation, Curr. Drug Targets, 2014, 15 (7), pp 720-728

http://dx.doi.org/10.2174/1389450115666140519162133


Kritika Chaudhari, Bashar Hamad, and Basharut A. Syed, Antithrombotic drugs market, Nat. Rev. Drug Discov., 201413 (8), pp 571–572

http://dx.doi.org/10.1038/nrd4365