[2015-Feb-23] FDA approves Farydak for treatment of multiple myeloma

[2015-Feb-23] FDA approves Farydak for treatment of multiple myeloma

http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm435296.htm

Farydak.cdx

M. Cecilia Crisanti, Africa F. Wallace, Veena Kapoor, Fabian Vandermeers, Melissa L. Dowling, Luana P. Pereira, Kara Coleman, Barbara G. Campling, Zvi G. Fridlender, Gary D. Kao and Steven M. Albelda, The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer, Mol. Cancer Ther., 2009, 8 (8), pp 2221-2231

http://dx.doi.org/10.1158/1535-7163.MCT-09-0138

Jessica E. Bolden, Melissa J. Peart and Ricky W. Johnstone, Anticancer activities of histone deacetylase inhibitors, Nat. Rev. Drug Discov., 2006, 5 (9), pp 769-784

http://dx.doi.org/10.1038/nrd2133